AIIMS Study Reveals That COVID-19 Infection Can Affect Semen Quality In Men

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Recently, the All India Institute of Medical Sciences (AIIMS) revealed a research study which said that the Wuhan Virus, also known as the Novel Coronavirus (COVID-19) infection could affect male semen.

The AIIMS conducted a study on 30 men and confirmed that SARS-CoV-2 (the Wuhan Virus) may negatively impact semen quality.  A team led by researchers at AIIMS Patna noted that COVID-19 can lead to multiorgan damage through the angiotensin-converting enzyme 2 receptor (ACE2), abundant in testicular tissue.  

It is to be noted, ACE2 acts as the receptor for the SARS CoV 2 spike protein, through which the virus gains entry into the host cells. 

The researchers also analysed the effect of the disease on semen quality and sperm DNA fragmentation index detecting potential sperm damage.

The authors of the research study said, “We conducted a real time reverse transcriptase test on all the semen samples.  Detailed semen analysis, including the sperm DNA fragmentation index, was done at first sampling that is during COVID-19.”   They further added, “After 74 days of the first sampling, we obtained the second sampling and repeated all the tests.”

The study, including researchers from AIIMS Managalagiri and AIIMS New Delhi, found that in the first sampling, semen volume, vitality, total motility, sperm concentration, and total sperm count were significantly lower in COVID-19 infected patients.

The study was published in the Cureus Journal of Medical Science.  

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